Christopher M Adams Selected Research

Basic-Leucine Zipper Transcription Factors

1/2020	Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ.
5/2017	Role of ATF4 in skeletal muscle atrophy.

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Christopher M Adams Research Topics

Disease

15	Atrophy 01/2022 - 04/2010
9	Muscular Atrophy (Muscle Atrophy) 01/2020 - 06/2011
5	Obesity 01/2021 - 11/2009
4	Narcolepsy 01/2019 - 07/2015
3	Macular Degeneration (Age-Related Maculopathy) 01/2022 - 01/2018
3	Glaucoma 01/2021 - 01/2018
2	Choroidal Neovascularization 01/2022 - 01/2018
2	Heart Failure 01/2022 - 08/2010
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2017
2	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2021 - 01/2017
2	Insulin Resistance 01/2017 - 01/2016
2	Muscle Weakness 11/2016 - 10/2015
2	Neoplasms (Cancer) 05/2016 - 09/2012
2	Pituitary ACTH Hypersecretion 12/2015 - 06/2015
2	Human Influenza (Influenza) 07/2015 - 07/2015
2	Metabolic Diseases (Metabolic Disease) 06/2015 - 06/2011
2	Hypertrophy 05/2014 - 06/2011
2	Starvation 04/2010 - 11/2009
1	Fibrosis (Cirrhosis) 01/2022
1	Cardiomyopathies (Cardiomyopathy) 01/2022
1	Ocular Hypertension (Glaucoma, Suspect) 01/2021
1	Open-Angle Glaucoma (Glaucoma, Open Angle) 01/2021
1	Lymphoma (Lymphomas) 12/2020
1	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 11/2020
1	Atypical Hemolytic Uremic Syndrome 11/2020
1	Cholera 10/2019
1	Arthritis (Polyarthritis) 01/2019
1	Hemolysis 01/2019
1	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2019
1	Pulmonary Hypertension 11/2017
1	Inflammation (Inflammations) 11/2017
1	Weight Gain 01/2017
1	Liver Diseases (Liver Disease) 01/2017
1	Chronic Renal Insufficiency 11/2016
1	Vascular Calcification 11/2016
1	Medulloblastoma 05/2016
1	Cerebellar Neoplasms 05/2016

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2010
9	Messenger RNA (mRNA)IBA 05/2016 - 04/2010
8	Activating Transcription Factor 4IBA 01/2022 - 04/2010
4	EnzymesIBA 01/2022 - 01/2015
4	pandemrixIBA 01/2019 - 07/2015
4	Ursolic AcidIBA 10/2015 - 06/2011
3	Orexin ReceptorsIBA 01/2019 - 07/2015
3	VaccinesIBA 01/2017 - 07/2015
3	tomatidineIBA 10/2015 - 05/2014
2	NADP (NADPH)IBA 01/2022 - 01/2021
2	acrizanibIBA 01/2022 - 01/2018
2	fibroblast growth factor 21IBA 01/2021 - 01/2017
2	Basic-Leucine Zipper Transcription FactorsIBA 01/2020 - 05/2017
2	AutoantibodiesIBA 01/2019 - 01/2017
2	Protein Kinases (Protein Kinase)IBA 05/2017 - 01/2016
2	Polyamine OxidaseIBA 05/2017 - 01/2015
2	OrexinsIBA 01/2017 - 07/2015
2	NucleoproteinsIBA 01/2017 - 07/2015
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2017 - 05/2014
2	RNA (Ribonucleic Acid)IBA 05/2016 - 04/2010
2	CarbohydratesIBA 01/2016 - 11/2009
2	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 12/2015 - 06/2015
2	OsilodrostatIBA 12/2015 - 06/2015
2	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2015 - 06/2015
2	Biomarkers (Surrogate Marker)IBA 12/2015 - 02/2015
2	AldosteroneIBA 06/2015 - 08/2010
2	MyogeninIBA 01/2015 - 10/2013
2	Transcription Factors (Transcription Factor)IBA 08/2014 - 04/2010
2	Glucose (Dextrose)FDA LinkGeneric 01/2012 - 11/2009
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2022
1	Glutathione (Reduced Glutathione)IBA 01/2022
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2022
1	MGV354IBA 01/2021
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2021
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2021
1	Complement System Proteins (Complement)IBA 11/2020
1	CCAAT-Enhancer-Binding ProteinsIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2019
1	Complement Factor B (Factor B)IBA 01/2019
1	AcidsIBA 01/2018
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2018
1	Soluble Guanylyl CyclaseIBA 01/2018
1	AntigensIBA 11/2017
1	deoxyuridine triphosphateIBA 11/2017
1	Interleukin-6 (Interleukin 6)IBA 11/2017
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2017
1	ApolipoproteinsIBA 01/2017
1	Asparaginase (Elspar)FDA Link 01/2017
1	Biological ProductsIBA 01/2017
1	Phosphotransferases (Kinase)IBA 01/2017
1	Eukaryotic Initiation Factor-2 (EIF 2)IBA 01/2017
1	Phosphates (Orthophosphate)IBA 11/2016
1	5' Untranslated Regions (5' UTR)IBA 05/2016

Therapy/Procedure

9	Therapeutics 01/2022 - 06/2011
3	Muscle Denervation 01/2015 - 08/2012
2	Denervation 01/2015 - 10/2013
1	Adjuvant Radiotherapy 12/2020
1	Cytoreduction Surgical Procedures 12/2020
1	Oral Administration 01/2019
1	Intravitreal Injections 01/2018
1	Topical Administration 01/2018
1	Injections 11/2017